A pilot holds a valid medical but knows of a new condition that would fail the exam. May they act as PIC?

No. A known medical deficiency grounds the pilot, even with a valid certificate.

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  1. No, not while they know of the condition ✔
  2. Yes, until the medical certificate expires
  3. Yes, if a passenger is also a pilot

Why: No pilot may act as PIC while they know or have reason to know of a medical condition that would make them unable to meet the medical certificate standards. The same applies to medication that disqualifies them.

Huh, didn't know that: The rule covers any required pilot flightcrew duty, not only acting as pilot in command.

The dad joke
I told my doctor I feel like an airplane. He said, 'You just need to take off for a few days.'
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References

Answer: No, not while they know of the condition. No pilot may act as PIC while they know or have reason to know of a medical condition that would make them unable to meet the medical certificate standards. The same applies to medication that disqualifies them.

  1. 14 CFR 61.53 Prohibition on operations during medical deficiency www.ecfr.gov/current/title-14/section-61.53
    no person who holds a medical certificate issued under part 67 of this chapter may act as pilot in command
    Checked 2026-10-09.
  2. 14 CFR 61.53 Prohibition on operations during medical deficiency www.ecfr.gov/current/title-14/section-61.53
    Knows or has reason to know of any medical condition that would make the person unable to meet the requirements for the medical certificate
    Checked 2026-10-09.

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