What over-the-counter supplement may help some travelers manage jet lag?

Melatonin, taken at the right time, may help shift your body clock.

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  1. Melatonin ✔
  2. Vitamin C
  3. Iron pills

Why: Melatonin is a hormone your brain makes in the dark. A small, well-timed dose can help shift your body clock, but ask a health provider first.

Huh, didn't know that: Taking melatonin at the wrong time can make the mismatch worse, so timing matters.

The dad joke
Melatonin and I have a deal: it helps me sleep, and I stop counting time zones instead of sheep.
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References

Answer: Melatonin. Melatonin is a hormone your brain makes in the dark. A small, well-timed dose can help shift your body clock, but ask a health provider first.

  1. Jet Lag Disorder (CDC Yellow Book) www.cdc.gov/yellow-book/hcp/travel-air-sea/jet-lag-disorder.html
    Appropriately timed light exposure in combination with melatonin may further facilitate adaptation.
    Checked 2026-10-12.

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